dafabet手机版登录 ｜ Department of Molecular & Cell Bio
The MCB Department is divided into five dafabet888手机版登录 that reflect general research areas. Department committees with representatives from each of the dafabet888手机版登录 offer the basis for governance, oversight of graduate affairs, overall curriculum, facilities, and such. However, each Division is in charge of its own course offerings, seminar series and annual retreat.
Biochemistry, Biophysics and Structural Biology
Cell & Developmental Biology
Genetics, Genomics and Development
Immunology and Pathogenesis
Faculty of the Division of Biochemistry, Biophysics and Structural Biology (BBS) are engaged in advanced study of the biological chemistry of cellular metabolites; enzymatic catalysis; the structure and function of biological macromolecules, especially nucleic acids and proteins; the supramolecular organization of complex cellular assemblies, including the transcription and DNA replication proteins, biological membranes; and, regulation of biological processes such as chromosomal folding, protein secretion and intracellular signaling. These problems are being investigated in systems that range from bacteria and bacteriophage to yeast to human cells and their viruses. Faculty of this division also participate in interdepartmental programs in structural biology, chemical biology, microbiology and toxicology. Facilities include those for protein-sequence analysis, peptide and oligonucleotide synthesis, access to the synchrotron at Lawrence Berkeley National Lab for X-ray crystallography, and NMR spectrometry. The Division holds a weekly seminar series by invited speakers, and each year is the host for the Chiron, Li, Stanier, and Wilson Lecturers. The Division holds its annual retreat at the Asilomar Conference Center in Pacific Grove, California, in early January.
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Faculty of the Division of Cell & Developmental Biology (CDB) pursue research aimed at detailed understanding of: the structure and function of cellular components, such as membranes, organelles, chromosomes and the cytoskeleton; cellular processes, such as epithelial transport, cell motility, mitosis, protein targeting and secretion, stem cell plasticity, and eukaryotic cell cycle control; tumor biology; cellular physiology; the origin of cell polarity; and the molecular and cellular basis for axis formation, morphogenetic movements, fate determination, and gene regulation during embryogenesis and cellular differentiation. These issues are being addressed in systems as diverse as yeast, fruit flies, worms, sea urchins, frogs, mice and mammalian cells in culture, and these studies exploit techniques ranging from molecular biology and microinjection to digital imaging and mathematical modeling. Specialized equipment for confocal fluorescence microscopy, video imaging, and computer simulations are available in shared core facilities in the Life Sciences Addition where many of the faculty are housed. The Division sponsors a weekly seminar series by invited speakers, holds informal journal clubs on topics in cell biology and holds its annual retreat at the Granlibakken Conference Center in Lake Tahoe, California, in the Fall Semester.